Both schools are really great. If you're into numbers, NYU is ranked 31 while Mt. Sinai is ranked 22 by US News and World. The area around NYU has great nightlife (lots of clubs, bars, restaurants, a movie theatre, a Borders store), in the "heart" of Manhattan, and has a younger vibe from the community. Mt Sinai is in the Upper East Side close to Harlem, but still a train ride away from the center of the city. How were your finaid packages from both schools? Mt Sinai's tuition is slightly cheaper than NYU. They both have great match lists, so you can't go wrong with either one, but it's a matter of personal preference.