Wayne is certainly the more established school, but the Beaumont health system is very strong and probably in a better place financially than the Henry Ford/DMC. I don't think either name soars above the other. Factors I would consider:
1. Cost
2. The different patient populations in Royal Oak and Detroit. Are you passionate about working with the underserved? Are you interested in emergency medicine?
3. Research opportunities - stronger at Wayne, though you could probably find clinical projects at OUWB too. OUWB requires that capstone project.
4. There are significant advantages to being part of a 100 person class (or whatever OUWB is now), rather than a 300 person class.
5. Fit--where would you honestly rather be, other factors aside? Would you rather live in Detroit or Oakland? I prefer Detroit, though Royal Oak is nice.
Personally, I was drawn more to Wayne.
@FlashMed13 , OUWB matched fine last year, but I didn't think it was a spectacularly impressive list. Something like half of the residents matched at Beaumont, which, though solid, makes me wonder if their other competitive options were limited. It's really hard to read match lists, though, especially when the class only had ~50 students.