Extreme examples:
Humbling experience: You get a 4.0/45T en route to applying for medical school. You go around telling the whole world you are undecided which ivy league school you are going to attend, even before secondaries arrive. You go to the interviews, act all conceited, pissing off the interviewers. You don't get into med school. You yell, b1tch, kill. Then, you cry. Then you are humble, reapply with some additional ECs, interview strong, and get in.
Ethical dilemma: You have two sisters. They are twins. Actually, they are clones (cool!). You have the exact same relationship with them in terms of how well you get along, etc. Then they both get sick and need a new liver. The liver transplant committee won't give you anything because your sisters have a life expectancy of about 35 years due to other, pre-existing issues. Then, amazingly, you find a liver on the side of the road that would be a functional transplant (sweet!). Who gets the liver?