Others will disagree with me, but here's my two cents.
Choose based on the criterion that will most impact you for the rest of your life, which is the cost of attendance. When you reach my stage of the game, you will be very happy if you choose based on price versus if you go to a more expensive school, because guess what, those loans come due while you're an intern. So my advice is to be brutally practical when you choose. That means you will need to hang on to all of your acceptances until you get your financial aid packages in March. For each school, look at the entire COA including living expenses, fees, etc., not just tuition. Don't forget to factor in grants, scholarships, and any other free financial aid.
If the schools you're deciding among cost within a few thousand dollars of one another per year, or if your parents can afford to pay for your tuition, first thank them profusely, and then ask them if they'd like to adopt me as your older sibling. But for serious, if money is not an issue, you can choose based on whatever criteria you want like geographic location or curriculum style. But I'd advocate for choosing based on gut feeling. Again, hold on to your acceptances for all real contenders until the spring, and go to all of the second looks. Choose the one that just feels right.
In the end, you can't make a bad decision, assuming you're deciding among two or more accredited American medical schools (MD or DO). The curricula of medical schools are highly regulated, and you will get a good education at any of them. So minimize your debt, and if cost is basically equal, then go wherever you feel like you'd be happiest.
