My $.02:
1. Read something about osteopathic medicine, in case somebody asks. A good summary:
http://www.westernu.edu/osteopathy-philosophy
(The founding principles, which constitute the "holistic" approach, sound like common sense and in fact have been assimilated and adopted by others, but they were novel at the time. Be aware that modern DO training is practically identical to MD training with the addition of OMM).
2. Read something about our healthcare problem and "Obamacare" - what, why, when. This is a common interview topic.
http://www.newyorker.com/reporting/2009/06/01/090601fa_fact_gawande?printable=true
http://online.wsj.com/article/SB10001424052702303644004577523260331816978.html
(This is not a political litmus test. The interviewer just wants to see if you know what's going on and how well you present an argument with fact-based reasoning).
3. Read something about medical ethics, which is another common topic. Lots of good sources on the web - for example:
http://www.dummies.com/how-to/content/medical-ethics-for-dummies-cheat-sheet.html
http://dept.lamar.edu/biology/preprofessional/Medical school interview 71404.htm
(The Lamar website has great questions and hypotheticals, but some are irrelevant and outdated - we now have a physician shortage, not surplus. Just pick what you can use).
4. Review your application materials. Get ready to tell your story. Your interviewers have some basic info about you and not much else. They don't know your GPA or MCAT score (and they probably don't care). They want to know that you like this school, you work hard and play well with others, and you have the capacity to persevere and succeed in med school and beyond as a physician.
5. Plan your trip - transportation, hotel, map, etc. Get a suit if you don't have one. Dress conservatively, like you're applying for a corporate job. Look nice and professional.
Good luck to everyone!