@Neon-turtle98 I recommend that you plan & decide as if you need to be in Galveston. It's important to do the small group things, anatomy, learning physical exam skills, and be a part of the class.
As much as instruction has become remote this year, I feel that med school is not a do-it-yourself project that can be successfully achieved fully in isolation.
3rd and 4th year away rotations are mainly in Houston and Tyler, some of them for core rotations like psychiatry and internal medicine, but you can't do all your rotations away from Galveston.
If being in more frequent contact with your wife is important, that could sway you to choose your Houston area option. If you choose Galveston, could she come join you most weekends?
Lots of things to consider & the two of you can discuss what will work for you.