Wayne State all the way and the cheaper tuition is only the most obvious reasoning why. I don't know much about Toledo, but I'd like to think that Wayne State's clinical experience is generally unrivaled. I've shadowed at Harper Hospital, and I like the "medical campus" that Wayne State has to offer. Additionally, I think the new Mazurek medical commons will serve as a useful tool in our medical training. I never got to check out those simulation labs with the dummy patients, but they seem pretty sweet. I'm not sure how the grading is done at Toledo, but for me personally, Wayne State's competitive-based grading curve is great. I'm assuming most of us here don't like to settle for B's, and we are only satisfied with A's. But the reality is that this is medical school; most of us won't be getting straight A's (they don't really have A's and B's at Wayne, but you know what it all translates into). Wayne's grading is pretty much the closest thing to a true curve, so this will bode well for someone like me who prides himself in doing better than the rest.
I guess the only downside to Wayne is that it is located in Detroit, but that comes hand in hand with good clinical experience. HOWEVA, we are comparing Detroit to Toledo which is kind of like comparing members of the Jackson family... they all are weird, have some history of crime, and I wouldn't let my kids near any of them no matter what time of the day it is.
If you are at all worried about safety, I would choose Toledo, but almost all Wayne State students would say that you don't have too much to worry about as a student.