Not a disadvantage, unless something changed and someone knows something I don't. At least up until this cycle, there has been no regional preference among our admissions, unless a candidate expressed a reason to NOT want to come to LA/CA. As with all CA schools, the apparent skew of students towards CA residents/CA undergrads is really just mostly due to disproportionate % people who have lived in CA wanting to stay in CA, not because our admissions looks at your birth place to decide whether to accept/waitlist/reject.